![]() ![]() Mention any other medications you are taking, including over-the-counter medications and herbal remedies, as these can also influence the risk of abnormal heart rhythms.If antibiotics are necessary, tell your doctor if you have a heart condition or a family history of one.Unless the doctor prescribes an antibiotic, don't ask for one. Don't push your doctor to prescribe a Z-Pak if you're battling a virus, not a bacterial infection.To help lower your odds of a Z-Pak problem, consider Dr. "Any risk that might be present is low in patients with heart disease or with risk factors for heart disease and very low for people without any predisposition to heart disease," says Dr. You'll have to talk to your doctor about whether Z-Pak is right for you. In part, this is why antibiotics should only be used when necessary-to treat infections caused by bacteria and not to treat colds caused by viruses." Should you still take Z-Pak? "Every medication can have side effects," he says. It's also prescribed far too often for the wrong reasons. ![]() Part of the reason why the Z-Pak presents a danger is because it's so widely used, says Dr. The result can range from a little dizziness and a fluttering in the chest to a seizure or sudden death if the heart is allowed to beat uncontrollably for too long. Prolonging the QT interval can make the heart beat in a chaotic fashion. The QT interval is, in simplest terms, the time your heart needs to recharge in between beats. Deepak Bhatt, a cardiologist at Harvard-affiliated Brigham and Women's Hospital. This can trigger abnormal heart rhythms in the lower chambers of the heart, says Dr. What's causing the riskĪzithromycin and other antibiotics in the same chemical class have the potential to prolong the QT interval on an electrocardiogram. To put this risk in perspective, there were 85 deaths per million courses of Z-Pak compared to 31 deaths per million courses of amoxicillin. Individuals with heart failure, diabetes or a previous heart attack, as well as those who have had bypass surgery or had stents implanted, were at even higher risk. The 14-year study, published last week in the New England Journal of Medicine, found that people taking azithromycin have a 2.5-fold increased chance of heart-related death within five days of starting a Z-Pak, compared to people taking the antibiotic amoxicillin. ![]() But a recent study suggests that the Z-Pak may do some harm even as it heals. If you've battled bronchitis or endured an ear infection, chances are good you were prescribed the antibiotic azithromycin (Zithromax), which is commonly available in a five-day dose known as the Z-Pak. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. Please note the date each article was posted or last reviewed. ARCHIVED CONTENT: As a service to our readers, Harvard Health Publishing provides access to our library of archived content.
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